Dr. Rhonda Patrick explains the blood-brain barrier. Individuals with early cognitive dysfunction develop brain capillary damage and BBB breakdown in the hippocampus irrespective of Alzheimer’s Aβ and/or tau biomarker changes, suggesting that BBB breakdown is an early biomarker of human cognitive dysfunction independent of Aβ and tau. Here is a discussion about this paper.… Continue reading Long term Cognition via a healthy intact Blood-Brain Barrier
Month: March 2023
NAD+ for Healthspan, Long-term Cognition, and Energy
Nicotinamide adenine dinucleotide (NAD+) plays a fundamental role in life and health through the regulation of energy biogenesis, redox homeostasis, cell metabolism, and the arbitration of cell survival via linkages to apoptosis and autophagic pathways. All sirtuins are NAD+ dependent. This Healthline piece suggests that “Research in humans has shown that NMN in doses… Continue reading NAD+ for Healthspan, Long-term Cognition, and Energy