Here are the dangers of high blood sugar:
Higher blood sugar means higher risk of dementia.
Blood sugar above 105 to 110 is a cognitive hazard.
High fasting glucose causes whole brain atrophy.
Keep blood sugar low to avoid oxidative stress.
Shown by a study of 240 healthy adults
Shown by a study of 266 men and women between the ages of 60 and 64.
Shown by 249 cognitively healthy non-diabetic individuals aged was 60-64.
Shown by a study of 210 cognitively healthy individuals (68–73 years).
Shown by a study of 2067 participants without dementia.
Shown by a study of 124 cognitively normal, non-diabetic adults with a family history of Alzheimer’s disease.
Shown by a study 249 people in their early 60s whose blood sugar was “high-normal”.
Shown by a study of 1,173 people, aged 75
Shown by a study of 2067 participants without dementia
Shown by a study of 5,189 people over 10 years.
Shown by a study of 104 healthy adults (ages 18 to 78) without diagnoses of diabetes or hypertension.
High after-meal (postprandial) blood glucose is a cognitive hazard.
Too much insulin can lead to neuroinflammation. Insulin is raised by eating sugar, and simple carbs.
Hyperglycemia results in reduced hippocampal microstructure.
Hyperglycemia increases amyloid-β levels.
Hyperglycemia increases susceptibility to amyloid-β toxicity.
High blood sugar results in abnormally low brain-derived neurotophic factor (BDNF).
High blood sugar injures via inhibition of MIF enzyme activity
Glycation (caused by high blood sugar) damages an enzyme called MIF (macrophage migration inhibitory factor).
Low blood sugar is also hazardous.
Hyperglycemia impairs neural activity in ways that are similar to what is observed in preclinical Alzheimer’s disease models.