Long Term Cognition via controlling Blood Pressure

 Normal blood pressure prevents brain shrinkage.

Hypertension can cause memory complaints even in young people.

Raised blood pressure at any age speeds cognitive decline.

Take heed of low diastolic pressure and blood pressure meds.

Two new studies support lowering systolic blood pressure to an intensive goal of 120 mm Hg.

Wide variations in blood pressure are also a concern.

Left ventricular hypertrophy (LVH) is bad news.

A study of 918 showed an increased risk of mild cognitive impairment.

High blood pressure slows the removal of waste from the brain.

High blood pressure injures by stiffening arteries ➝ silent strokes.

A study of 147 show increase amyloid buildup in those genetically predisposed and hypertensive.

Blood pressure variability is important – too much is bad.

Normal blood pressure prevents small vessel disease which may cause Alzheimer’s.

Especially bad is late life high blood pressure: white matter lesions and cerebral microbleeds.

Hypertension alters the structure of cerebral blood vessels and disrupts intricate and disrupts intricate vasoregulatory mechanisms that assure an adequate blood supply to the brain.

The brain relies on continuous delivery of blood flow to its active regions in accordance with their dynamic metabolic needs. Hypertension disrupts these vital regulatory mechanisms, leading to the neuronal dysfunction and damage underlying cognitive impairment.

Compared to a person with a high blood pressure of 135/85, someone with an optimal reading of 110/70 was found to have a brain age that appears more than six months younger by the time they reach middle age. By detecting the impact of increased blood pressure on the brain health of people in their 40s and older, we have to assume the effects of elevated blood pressure must build up over many years and could start in their 20s. This means that a young person’s brain is already vulnerable.

Normal blood pressure prevents vascular dementia.

Lifestyle modification is better than meds.
Time-restricted eating in the form of eating only early in the day may help control blood pressure.

If one must use a drug, angiotensin receptor blockers seem best.

Combined uridine and choline helped hypertensive rats.

Blood pressure meds may not help avoid dementia, or they might help, especially if intervention happens early. This might reduce structural damage to the brain.

Nilvadipine is an example of a blood pressure drug that might help.

See the blood pressure dietary/lifestyle suggestions in this blog post.

Chronic low blood pressure is also a cognitive threat. Strong calf muscles may help.

By Otto

I am a health enthusiast, engineer, and maker.

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