Hypertension can cause memory complaints even in young people.
Raised blood pressure at any age speeds cognitive decline.
Two new studies support lowering systolic blood pressure to an intensive goal of 120 mm Hg.
Wide variations in blood pressure are also a concern.
Left ventricular hypertrophy (LVH) is bad news.
A study of 918 showed an increased risk of mild cognitive impairment.
High blood pressure slows the removal of waste from the brain.
High blood pressure injures by stiffening arteries ➝ silent strokes.
A study of 147 show increase amyloid buildup in those genetically predisposed and hypertensive.
Blood pressure variability is important – too much is bad.
Hypertension alters the structure of cerebral blood vessels and disrupts intricate and disrupts intricate vasoregulatory mechanisms that assure an adequate blood supply to the brain.
The brain relies on continuous delivery of blood flow to its active regions in accordance with their dynamic metabolic needs. Hypertension disrupts these vital regulatory mechanisms, leading to the neuronal dysfunction and damage underlying cognitive impairment.
Compared to a person with a high blood pressure of 135/85, someone with an optimal reading of 110/70 was found to have a brain age that appears more than six months younger by the time they reach middle age. By detecting the impact of increased blood pressure on the brain health of people in their 40s and older, we have to assume the effects of elevated blood pressure must build up over many years and could start in their 20s. This means that a young person’s brain is already vulnerable.
Lifestyle modification is better than meds.
Combined uridine and choline helped hypertensive rats.
Nilvadipine is an example of a blood pressure drug that might help.
See the blood pressure dietary/lifestyle suggestions in this blog post.
Chronic low blood pressure is also a cognitive threat. Strong calf muscles may help.