Copper appears to be one of the main environmental factors that trigger the onset and enhance the progression of Alzheimer’s disease by preventing the clearance and accelerating the accumulation of toxic proteins in the brain.
Alzheimer’s disease was virtually unknown 100 years ago. And it involves only developed countries that use copper plumbing. Something in our environment associated with development is poisoning the minds of our aged. The epidemic is associated with the use of copper plumbing, and the taking of copper in multi-mineral supplements. Food copper (organic copper) is processed by the liver and is transported and sequestered in a safe manner. Inorganic copper, such as that in drinking water and copper supplements, largely bypasses the liver and enters the free copper pool of the blood directly. This copper is potentially toxic because it may penetrate the blood/brain barrier.
Don’t supplement: pills may cause copper imbalance, and are likely to be copper-2. Cocoa/chocolate is a terrific way to make sure you have sufficient dietary copper.
Copper is especially hazardous for those over 50.
Copper deficiency is rare.
Meat can be a major dietary source of excess copper. Eating large amounts of meat may increase Alzheimer’s disease risk is by increasing your intake of trace metals, such as copper and iron, that in excess have been shown to promote oxidative damage – particularly in older adults.
Copper plumbing is suspect, and is a source of copper-2.
Copper in combination with saturated fat is especially toxic.
Copper can compromise the blood-brain barrier.
Copper can inhibit amyloid clearance and cause neuroinflammation.
Researchers found tiny deposits of elemental copper and iron in the brains of Alzheimer’s patients.
A reverse osmosis water purification system can remove most copper from drinking water.
To help protect against copper toxicity:
Capsaicin may protect one from copper-induced oxidation.
Curcumin protects from copper injury in vitro.
Curcumin reduced the DNA damage induced by copper in mice.
Curcumin reduced the oxidative injury induced by copper in rats.
Vitamin E is generally protective against Cu-induced oxidative damage. Do not supplement vitamin E.
Copper gluconate may possess carcinogenic risks for the liver and forestomach at high dose level, and co-administered green tea catechins exerted preventive effects in rats.
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