Heart Health

Heart health supports health span, brain health, and vitality. Here are a few suggestions.   Eating a plant-based diet at any age may lower cardiovascular risk. People can choose among plant foods that are as close to natural as possible, not highly processed. More plant foods mean less risk. The most dangerous plaques go away within weeks on a plant-based diet. Numerous… Continue reading Heart Health

Quacks and Snake Oil

Let us start with this illuminating video entitled Why Do People Keep Falling For Things That Don’t Work? Here is some reasons why: Confirmation bias – where you ignore evidence that contradicts your belief, and place more value on evidence that supports it. Here is Tim Minchin on confirmation bias. Mis-attributing causation between two events… Continue reading Quacks and Snake Oil

Long-Term Cognition via Melatonin

Melatonin is a pleiotropic neurohormone controlling many physiological processes and whose dysfunction may contribute to several different diseases, such as neurodegenerative diseases, circadian and mood disorders, insomnia, type 2 diabetes and pain. Melatonin can have side effects.   The circadian production of pineal melatonin is controlled by endogenous oscillators within the suprachiasmatic nucleus (SCN) and… Continue reading Long-Term Cognition via Melatonin

List of blog posts

Alcohol consumption is a cognitive, heart, and cancer threat.   Amyotrophic lateral sclerosis (ALS).   Autophagy for longevity and long-term cognition.   Blood Pressure control (below 120 systolic) to prevent dementia, for kidney health, for cardiovascular health. and for longevity.   Blood Sugar control for long-term cognition.   Blood-brain barrier dysfunction can precede symptoms of… Continue reading List of blog posts

ALS (amyotrophic lateral sclerosis)

Amyotrophic lateral sclerosis (ALS) is an incurable neurodegenerative disease resulting in progressive weakness and selective degeneration of the motor neurons, leading to death from respiratory failure within 3–4 years [1], though 10% of people with ALS will live ten years or longer. The onset of amyotrophic lateral sclerosis (ALS) is more common in adults over… Continue reading ALS (amyotrophic lateral sclerosis)

Mitochondrial Health

Every cell contains hundreds of mitochondria, each with its own genome, mitochondrial DNA separate from that of the cell nucleus. The primary role of mitochondria is to generate chemical energy store molecules, adenosine triphosphate (ATP), used to power cell activities. Mitochondrial dysfunction with aging isn’t just a loss of ATP generation and production of a harmful amount of reactive oxygen species, however. It… Continue reading Mitochondrial Health

Selected Supplements for Immunity, Energy, Long-term Cognition, and Health Span.

First considerations: dietary supplements have not been used for most of human history. There are areas of the world where people live extraordinary long, healthy lives. They do not achieve this by taking dietary supplements.     Nutrients required for the function of longevity proteins constitute a class of vitamins that are here named “longevity… Continue reading Selected Supplements for Immunity, Energy, Long-term Cognition, and Health Span.

Polyhenols for Healthspan and Long-term cognition

Health benefits of phenolic compounds From Medical News Today: Polyphenols may improve rheumatoid arthritis through mitogen-activated protein kinase (MAPK) inhibition. In addition, plant-derived polyphenols can reduce depression, inflammation, and oxidative stress.     Quercetin and epicatechin (EC) decrease atherosclerosis by augmenting nitric oxide (NO) activity and decreasing serological endothelin-1 levels. Quercetin, which can be obtained… Continue reading Polyhenols for Healthspan and Long-term cognition

The Incredible Danger of Sugar Overconsumption

Dr. Mike Hansen pointed out this systematic reviews and meta-analyses of randomised controlled trials. This included 73 meta-analyses and 83 health outcomes from 8601 unique articles, including 74 unique outcomes in meta-analyses of observational studies and nine unique outcomes in meta-analyses of randomised controlled trials. The results: Significant harmful associations between dietary sugar consumption and… Continue reading The Incredible Danger of Sugar Overconsumption

Long term Cognition via a healthy intact Blood-Brain Barrier

Dr. Rhonda Patrick explains the blood-brain barrier.   Individuals with early cognitive dysfunction develop brain capillary damage and BBB breakdown in the hippocampus irrespective of Alzheimer’s Aβ and/or tau biomarker changes, suggesting that BBB breakdown is an early biomarker of human cognitive dysfunction independent of Aβ and tau. Here is a discussion about this paper.… Continue reading Long term Cognition via a healthy intact Blood-Brain Barrier